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Breast Cancer Recurrence – Death & Vitamin D

Filed under: Women — Tags: , , , , — @ 1:11 am September 25, 2011

Based upon recent clinical research findings, Vitamin D is the only remaining vitamin that may have significant cancer and cardiovascular disease prevention properties. Recent large-scale prospective randomized clinical research trials have not only failed to identify a cancer prevention role (beyond a healthy balanced diet) for Vitamin E, Vitamin C, folate, and beta-carotene (a member of the Vitamin A family) supplements, but data from these trials have strongly suggested an increased risk of adverse health outcomes, at least in some sub-groups of patients, with supplements of several of these vitamins.

Alas, as is typically the case with public health studies, the clinical data regarding Vitamin D is not without inconsistency, and the data on Vitamin D and cancer incidence has not been uniformly positive, either. However, multiple recent epidemiological and prospective clinical research studies have at least suggested that low levels of Vitamin D in our bodies may, in fact, be associated with a higher risk of developing certain cancers (look for a more comprehensive review of the data on Vitamin D and cancer prevention in my forthcoming book, “A Cancer Prevention Guide for the Human Race”).

Moreover, decreased blood levels of Vitamin D also appear to be linked to an increased risk of cardiovascular disease as well.

Now, a newly published prospective clinical research trial suggests that decreased levels of Vitamin D in the blood appears to be associated with an increased risk of breast cancer recurrence, and death due to breast cancer, in women previously diagnosed with early stage breast cancer. In this study, which has just been published in the Journal of Clinical Oncology, 512 women with early-stage breast cancer, diagnosed between 1989 and 1996, were prospectively followed for an average of nearly 12 years.

Blood was routinely collected from all women following their diagnosis of breast cancer, as a part of this clinical research trial. The women were then closely followed for recurrence of their breast cancer, and for death due to breast cancer and other causes.

As with other similar studies, a surprisingly large number of these otherwise healthy women were discovered to have decreased levels of Vitamin D in their blood. In 38 percent of these women, Vitamin D levels were significantly below normal levels, while another 39 percent of these women had mildly decreased levels of circulating Vitamin D. Among these 512 women, 116 experienced metastatic recurrence of their breast cancer during the course of this prospective clinical study, while 87 women died with evidence of recurrent breast cancer.

The results of this prospective clinical study were rather compelling. The 10-year survival rates for these women with early-stage breast cancer varied significantly according to the level of Vitamin D in their blood. Survival at 10 years following breast cancer diagnosis was 74 percent, 85 percent, and 85 percent for women with significantly deficient, mildly deficient, and normal Vitamin D levels, respectively. Based upon the analysis of all of the data from this study, breast cancer patients with a significant deficiency of Vitamin D were observed to be almost twice as likely (71 percent increased risk) to experience a recurrence of their breast cancer, and they were 60 percent more likely to die, when compared to the patients who had normal levels of Vitamin D in their blood.

Although this clinical study included relatively few patients, it does, nonetheless, raise the possibility that a significant deficiency of Vitamin D may be associated with a worse prognosis in patients with early-stage breast cancer. Another related finding in this study was that very low levels of Vitamin D also appeared to be associated with breast tumors with more aggressive features when examined under the microscope, which is consistent with other studies that have suggested a link between “high grade” breast tumors and decreased blood levels of Vitamin D. At the same time, as I have already mentioned, the available data regarding Vitamin D levels (and the use of Vitamin D supplements) has not been consistent, and other clinical studies have failed to identify a link between Vitamin D and breast cancer risk. There is also some experimental data available suggesting that very high levels of Vitamin D in the blood may also be associated with poorer outcomes in women with breast cancer (similar findings have also been reported for excessive Vitamin D levels and cardiovascular disease outcomes). Taken together, the data from these various studies strongly suggest that there may be a fairly narrow “optimal range” of Vitamin D levels in the blood that are associated with a decreased risk of breast cancer, a decreased risk of breast cancer recurrence (and death), and a decreased risk of cardiovascular disease; and that excessively high or low levels of this vitamin may have adverse health effects in these areas.

The next obvious step is to conduct larger prospective clinical research trials that secretly randomize patient volunteers to receive various doses of Vitamin D, versus placebo (sugar) pills. There are several such studies already underway (or about to start), involving both cancer patients and patients without cancers. However, it will likely take another 10 years for mature data to emerge from these ongoing studies. Meanwhile, my advice is to eat a healthy and well-balanced diet. If you are a breast or prostate or colorectal cancer survivor, or if you have one or more risk factors for these cancers (or for cardiovascular disease), then you may also want to ask your physician to measure the level of active Vitamin D in your blood. If you are significantly deficient in Vitamin D, then your physician might consider the possibility of Vitamin D supplementation in conjunction with careful serial monitoring of your Vitamin D levels.
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Disclaimer: As always, my advice to readers is to seek the advice of your physician before making any significant changes in medications, diet, or level of physical activity.
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Dr. Wascher is an oncologic surgeon, a professor of surgery, a widely published author, and a Surgical Oncologist at the Kaiser Permanente healthcare system in Orange County, California.

The Breast Defense Against Violence: Ban the Bra!

As the world recognizes the United Nations’ International Day for the Elimination of Violence Against Women, one form of violence has been overlooked that happens everyday, all over the world, and causes pain, suffering, disfigurement, and even death to thousands of women annually. And women actually do it to themselves. It is something they do out of fear of rejection and ridicule. It is the ultimate form of psychological violence, a form of self abuse to conform to the demands of men.

I am referring to breast disease and cancer, and how it is caused by the wearing of tight bras.

Most women agree that their bras are uncomfortable. However, the demand for acceptance trumps all reason, as women eagerly spend billions of dollars annually to display their cleavage to the pleasure of men.

Creating cleavage and a perky, youthful bustline, however, has a price. To get the “right” look, the bra must be tight, as it compresses the soft breast tissue. This causes pain, cysts, and can lead to cancer, something that was rare prior to the advent of the bra.

It is nothing new for women to abuse themselves for fashion. For example, not long ago, Chinese women bound their feet to please their men. Foot binding was disabling, causing completely distorted feet and toes. Some toes would actually rot off. Men would find erotic pleasure unwrapping, cleaning, and re-wrapping their women’s feet. And this went on for centuries!

Another senseless fashion, the wearing of corsets, also tortured women for centuries. The tight lacing impaired breathing, digestion, kidney function, and blood and lymphatic circulation, and caused pelvic disease and permanent skeletal deformation. But men loved the hourglass look, so women put up with the abuse.

Fashions can be sick. And this also applies to the wearing of bras.

Bras are constrictive by design. Their purpose is to alter breast shape, and this requires constant pressure applied to the soft breast tissue. Pressure, however, impairs the circulation of blood and lymph within the breast tissue. Most effected are the tiny, easily compressed lymphatic vessels, which drain the tissue of lymph fluid and is the circulatory pathway of the immune system.

Lymph fluid bathes the cells and needs to be regularly cleansed, taking with it toxins, waste products, viruses, cancer cells, bacteria, and cell debris. This lymph fluid is brought via lymphatic vessels to lymph nodes, which filter the fluid and mount an immune response, if needed. Eventually, the fluid re-enters the bloodstream. However, if the breast is constricted by a tight bra, the lymphatic vessels can be compressed, causing the fluid to accumulate in the tissue, along with the toxins it was trying to eliminate, some of which are carcinogenic. The result is pain, cyst formation, fibrocystic breast disease, toxification of the breast tissue, and, ultimately, cancer. Red marks and indentations in the skin left by the bra are telltale signs of constriction.

But will women eliminate their bras? Some women do once they hear about the bra/cancer link. However, for many, the fear of cancer and the pain of constriction are not as compelling as the fear and pain of rejection. To feel accepted, some women accept the self abuse of bra wearing. Some even pay a surgeon to cut their breasts, enlarging or reducing their size, subjecting themselves to the risks of surgery, anesthesia, and potential complications, all to look acceptable to others.

This is violence against women masquerading as fashion. That women do this violence to themselves makes it more disturbing. If a man were to punch a women in the breast, it would be obvious violence. When a woman binds her breasts to the point of pain, cysts, and cancer, it is still violence, even if the bra is lacy, sexy, and fashionable.

Sydney Ross Singer is a medical anthropologist and director of the Institute for the Study of Culturogenic Disease, located in Hawaii. His unique form of applied medical anthropology searches for the cultural/lifestyle causes of disease. His working assumption is that our bodies were made to be healthy, but our culture and the attitudes and behaviors it instills in us can get in the way of health. By eliminating these causes, the body is allowed to heal. Since most diseases of our time are caused by our culture/lifestyle, this approach has resulted in many original discoveries into the cause, and cure, of many common diseases. It also makes prevention possible by eliminating adverse lifestyle practices. Sydney works with his co-researcher and wife, Soma Grismaijer, and is the author of several groundbreaking health books, including the acclaimed book, Dressed To Kill: The Link Between Breast Cancer and Bras (Avery/Penguin Putnam, 1995; ISCD Press, 2005).

Sydney Ross Singer and Soma Grismaijer can be reached at the Institute for the Study of Culturogenic Disease, P.O. Box 1880, Pahoa, Hawaii 96778 (808) 935-5563. Also visit their website at http://www.SelfStudyCenter.org, where you can try lifestyle self studies to prevent and cure numerous diseases.

People saved from the brink of death by the one-minute cure..

Filed under: Herbal Breast Actives — Tags: , , , , , — libertees @ 4:19 pm November 23, 2009

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© 2003-2009 World Marketing Media, Inc.

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JanuszJanulis
© 2003-2009 World Marketing Media, Inc.

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